After the first chamber / shell, the nesting platonics begin. Most elements experience a varying state of chamber cohesion: inner shells spin independently from outer, in varying degrees. This, in combination with the element’s position in its platonic chamber, determines many of its bonding capabilities and chemical family it resides in.
The noble gases outer shell (after Helium) are locked with the previous inner shell. For example, Neon: the inner dual paired tetrahedron with 8 vertices brings us to Oxygen. Add 2 more proton/electron pairs in the 2nd outer shell, and we have a total of 10 – Neon. Those 2 outer proton/electron pairs are directly opposite each other, creating the maximum force for a small radius, as well as having a tendency to lock with the inner shell. It is the combination of these 2 things that prevent Neon (and all the nobles) from bonding with other elements.